_zope_hookable.pyd is a module\r, a process file that works with the Zope programming application.  This file is commonly found in the Windows registry, which contains short cuts to help programs work faster.  It is commonly found in %programfiles%\plone 3\zope\lib\python\zope\hookable, or in a similarly structured file path.

_zope_hookable.pyd is not a malicious program, but it can become corrupted by programs that are.  Registry entries in general can become corrupt or outdated with time, slowing a computer through no fault of the owner’s.  ZookaWare PC Cleaner offers a free scan to find such errors and keep a computer running smoothly.