_zope_proxy_proxy.pyd is a Python-language file used by the Zope application server.  Zope is a software framework used to run applications on many websites.

If you are seeing error messages about _zope_proxy_proxy.pyd, it could be that your Windows registry lacks the file and needs it.  The file could have become corrupt due to spyware or a virus.  Or it could just be out of date.

The Windows registry collects all the process files from the programs on a computer and organizes them to run in a single place.  Without it, the computer would become horribly slow.  But a computer can also become slow when something is incorrect or missing in the registry.  Anti-virus programs rarely fix this kind of problem.

Monthly or weekly scans with a registry cleaner are essential to keeping this database in order.  Interested parties may obtain a free scan from ZookaWare PC Cleaner.