~is3.tmp is a temporary file.  It belongs to the IP*Works toolkit used for Internet development.

It is unlikely that this file is actively harmful.  However, since it is a temporary file, it likely does not need to remain on a system for long and may end up crowding the Windows registry.

The Windows registry gathers all of the process files of the programs on a computer.  It bundles them together and directs them to the correct programs and interfaces.

The Windows registry keeps a system running smoothly and quickly.  However, a cluttered or damaged registry can cause the computer to run slowly, or even crash.

~is3.tmp and other temporary files can potentially clutter up a registry.  The best way to take care of this is either to run a registry cleaner or take care of it yourself.  Users should use extra caution if editing these files on their own, as deleting the wrong file can cause the whole system to stop working.

Interested parties can get a free scan with the ZookaWare PC Cleaner registry cleaner.